Innovative Treatment Modalities: search for a cure: Hormone and chemotherapy targets

Promising leads from biology-based studies are encouraged to begin the critical path to clinical translation. Examples include immunotherapy, delivery technologies, gene therapy, new drug development/testing, and new approaches to clinical decision-making


Compounds Blocking Assembly of LRH-1 in Breast Cancer 2009 (Cycle 15)
  University of California, San Francisco   $90,000
  Award Type: Postdoctoral Fellowship
 
Targeting DNA Repair Function of Breast Cancer Stem Cells 2009 (Cycle 15)
  Scripps Research Institute   $284,850
  Award Type: IDEA
 
Membrane-associated Estrogen Receptors in Breast Cancer 2009 (Cycle 15)
  University of California, Los Angeles   $150,000
  Award Type: IDEA
 
Determinants of Response to Microtubule Stabilizing Drugs 2007 (Cycle 13)
  Stanford University   $66,302
  Award Type: Postdoctoral Fellowship
 
Polyamide Inhibitors to Block Estrogen Receptor Function 2007 (Cycle 13)
  California Institute of Technology   $75,600
  Award Type: Dissertation
 
Mechanisms of HSP90 Inhibitor Action in Breast Cancer 2007 (Cycle 13)
  Beckman Research Institute of the City of Hope   $67,871
  Award Type: Dissertation
 
A Targeted Therapy for Wound-like Breast Cancers 2006 (Cycle 12)
  Stanford University   $232,934
  Award Type: IDEA
 
Topoisomerase-IIa as a Predictor of Anthracycline Response 2006 (Cycle 12)
  University of Southern California   $244,499
  Award Type: IDEA
 
Inhibition of Breast Cancer Aggressiveness by Cannabidiol 2006 (Cycle 12)
  California Pacific Medical Center Research Institute   $183,000
  Award Type: IDEA
 
Breast Tumor Inhibition by Vitamin D in a Mouse Model 2006 (Cycle 12)
  Stanford University   $234,388
  Award Type: IDEA
 
Artemisinin Disrupts Estrogen Receptor-Alpha and Cell Growth 2006 (Cycle 12)
  University of California, Berkeley   $100,000
  Award Type: IDEA
 
Sulforaphane: Its Potential for Treatment of Breast Cancer 2006 (Cycle 12)
  University of California, Santa Barbara   $65,415
  Award Type: Dissertation
 
An Approach to Antiestrogen Resistance in Breast Cancer 2005 (Cycle 11)
  University of California, San Diego   $132,860
  Award Type: Postdoctoral Fellowship
 
Apogossypol Derivatives for Breast Cancer Therapy 2004 (Cycle 10)
  The Burnham Institute for Medical Research   $285,764
  Award Type: STEP
 
Chinese Herb/Chemotherapy Interactions in Breast Cancer 2003 (Cycle IX)
  University of California, San Francisco   $200,000
  Award Type: STEP
 
Chemotherapy-Induced Ovarian Damage: Prevention and Impact 2002 (Cycle VIII)
  University of California, San Francisco   $64,189
  Award Type: CRC Pilot
 
Clotting Breast Cancer 2002 (Cycle VIII)
  University of California, Irvine   $98,986
  Award Type: IDEA
 
Dietary Indole Effect on Estrogen Urinary Metabolites 2001 (Cycle VII)
  University of California, Berkeley   $89,925
  Award Type: TRC Pilot
 
Patient-Individualized Chemotherapy in Breast Cancer 2001 (Cycle VII)
  University of California, Los Angeles   $296,994
  Award Type: New Investigator
 
Novel Technologies to Identify Tissue-Selective Estrogens 2001 (Cycle VII)
  University of California, San Francisco   $75,000
  Award Type: IDEA
 
In Vivo Effects of Chinese Herbal Extracts on Breast Cancer 2001 (Cycle VII)
  University of California, San Francisco   $199,600
  Award Type: STEP
 
A New Class of Drugs to Treat Breast Cancer 2000 (Cycle VI)
  University of California, San Francisco   $33,694
  Award Type: Postdoctoral Fellowship
 
Identifying the Breast Cancer Target for Indole-3-Carbinol 2000 (Cycle VI)
  University of California, Berkeley   $40,000
  Award Type: Postdoctoral Fellowship
 
Targeted Chemotherapy to Treat Breast Cancer 2000 (Cycle VI)
  University of California, San Francisco   $200,000
  Award Type: IDEAS II
 
Role of p14ARF in Metastatic Breast Cancer 2000 (Cycle VI)
  Sidney Kimmel Cancer Center   $365,000
  Award Type: IDEAS II
 
Novel Agents for Treatment of Advanced Breast Cancer 2000 (Cycle VI)
  SRI International   $388,866
  Award Type: IDEAS II
 
Indole Derivatives as Novel Breast Cancer Therapeutics 1999 (Cycle V)
  University of California, Berkeley   $150,000
  Award Type: IDEAS II
 
How Indole-3 Carbinol Inhibits Breast Cancer Cell Growth 1999 (Cycle V)
  University of California, Berkeley   $35,000
  Award Type: Postdoctoral Fellowship
 
Biologic Determinants of Response to Paclitaxel & Radiation 1998 (Cycle IV)
  University of Southern California   $595,661
  Award Type: TRC Full
 
Biological Determinants of Response to Paclitaxel and Radiat 1998 (Cycle IV)
  Molecular Medicine Research Institute   $0
  Award Type: TRC Full
 
Biological Determinants of Response to Paclitaxel and Radiat 1998 (Cycle IV)
  Molecular Medicine Research Institute   $0
  Award Type: TRC Full
 
Inhibitors of the Breast Cancer Her-2/neu Gene 1997 (Cycle III)
  Scripps Research Institute   $342,796
  Award Type: ITaMoCAs
 
Enhancing breast cancer sensitivity to chemotherapy 1997 (Cycle III)
  Sidney Kimmel Cancer Center   $380,825
  Award Type: ITaMoCAs
 
Biochemical Correlates for Clinical Response to Paclitaxel 1997 (Cycle III)
  University of Southern California   $110,390
  Award Type: TRC Pilot
 
Architecture of the ErbB2 Molecule Leading to Breast Cancer 1996 (Cycle II)
  University of California, San Francisco   $222,349
  Award Type: New Investigator
 
Understanding Tamoxifen - A Drug for Breast Cancer 1995 (Cycle I)
  University of California, San Francisco   $225,000
  Award Type: New Investigator
 
New Endocrine Strategy to Prevent Breast Cancer Progression 1995 (Cycle I)
  University of California, Los Angeles   $263,080
  Award Type: Research Project