Summary of 1999 Research Awards

1999 was the California Breast Cancer Research Program's fifth year of operation, and marked another year of important achievements and growth for the BCRP. With a budget of $17,432,000, BCRP was able to award 62 new projects across the state. The projects include work in the areas of:

California Institute of Technology

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Brown, Eric
Role of a DNA Damage Response Gene in Breast Cancer

2.0

$70,000

$0

$70,000

 

California Pacific Medical Center Research Institute

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Desprez, Pierre-Yves
Id-1 Expression During Breast Cancer Progression

1.0

$49,988

$28,043

$78,031

Singh, Jarnail
Identification of Novel Id-1 Regulated Genes in Breast Cells

2.0

$70,000

$5,600

$75,600

SUBTOTAL

 

$119,988

$33,634

$153,631

 

Cedars-Sinai Medical Center

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Davis, Vicki
Breast Cancer Prevention by a Dominant Negative ER Variant

2.0

$199,989

$102,994

$302,983

Koeffler, H. Phillip
Identification of Novel Secreted Proteins of Breast Cancer

1.0

$50,000

$25,750

$75,750

SUBTOTAL

 

$249,989

$128,744

$378,733

 

City of Hope National Medical Center

DURATION

DIRECT COST

INDIRECT COST

TOTAL

MacDonald, Deborah
Communication, Content & Impact of Genetics in Breast Cancer

3.0

$427,442

$203,732

$631,174

 

John Wayne Cancer Institute

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Hoon, Dave
Clinical Utility of Breast Cancer DNA Markers in Plasma

2.0

$197,762

$175,613

$373,375

 

Kaiser Permanente Southern California

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Enger, Shelley
Can Molecular Markers Predict Response to Adjuvant Therapy?

3.0

$206,166

$66,486

$272,652

 

La Loba Support Group

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Kreshka, Mary Anne
(Sub-contract to Stanford University)

3.0

$0

$0

$0

 

Lawrence Berkeley National Laboratory

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Hagios, Carmen
Hox Genes in Normal Breast Development and Breast Cancer

2.0

$70,000

$0

$70,000

 

Lawrence Livermore National Laboratory

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Albala, Joanna
A Role for Rad51B in Breast Cancer

3.0

$225,000

$182,787

$407,787

 

Marin Breast Cancer Watch

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Farren, Georgianna
Marin County Breast Cancer Study of Adolescet Risk Factors

2.5

$215,000

$31,800

$246,800

 

Molecular Medicine Research Institute

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Beyene, Yewoubdar
Belief and Risks of Breast Cancer Among African Immigrants

2.0

$236,873

$0

$236,873

 

The Orange County Asian and Pacific Islander Community Alliance

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Mary Anne Foo / Sora Park Tanjasiri
Belief and Risks of Breast Cancer Among African Immigrants
(Sub-contract to University of California, Los Aneles)

3.0

$0

$0

$0

 

Salk Institute for Biological Studies

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Xie, Wen
ACTR/A1B1 in Mammary Gland Development and Tumorigenesis

2.0

$70,000

$5,600

$75,600

 

Scripps Research Institute

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Felding-Habermann, Brunhilde
Breast Cancer Cell Binding to the Endothelium

2.0

$197,759

$129,133

$326,892

Jackson, Janis
Specificity of Ras Signaling in Breast Cancer

2.0

$150,000

$114,450

$264,450

Strohmaier, Heimo
Proteolysis of Cyclin E in Normal and Malignant Breast Cells

2.0

$70,000

$5,600

$75,600

Wang, Xiaofei
Mechanism of Radiosensitivity in Breast Cancer Cells

2.0

$70,000

$5,600

$75,600

SUBTOTAL

 

$487,759

$254,783

$742,542

 

Sidney Kimmel Cancer Center

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Schnitzer, Jan
Targeting Breast Cancer Blood Vessels

2.0

$200,000

$192,600

$392,600

 

Stanford University

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Cordova, Matthew
Do Community Cancer Groups Enhance Well-being?

2.0

$70,000

$5,600

$75,600

Hancock, Steven
Breast Cancer Screening in Women Surviving Hodgkin's Disease

3.0

$716,626

$319,320

$1,035,946

Jackson, Peter
Role of the POP1 Gene in Breast Cancer Genomic Stability

1.0

$75,000

$41,535

$116,535

Jeffrey, Stefanie
Breast Cancer Gene Expression Using Amplified Core Biopsie

1.0

$100,000

$58,500

$158,500

Koopman, Cheryl
A Support Group Alternative for Rural and Isolated Women

3.0

$491,009

$97,322

$588,331

Thompson, Devon
Characterization of hAG-2 and Its Role in Breast Cancer

3.0

$225,000

$130,749

$355,749

Weigel, Ronald
GATA-3 Expression of Hormone Responsive Breast Cancer

2.0

$150,000

$84,825

$234,825

Zhang, Hong
Cloning of Senescence Genes in Mammary Epithelial Cells

2.0

$70,000

$5,600

$75,600

SUBTOTAL

 

$1,897,635

$743,451

$2,641,086

 

The Burnham Institute

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Ely, Kathryn
Molecular Structure of BAG-1: a New Protein in Breast Cancer

2.0

$149,630

$142,148

$291,778

Kim, Youngsoo
COX-2 and Apoptosis Regulation in Breast Cancer

2.0

$70,000

$5,600

$75,600

Pasquale, Elena
Role of the EphB4 Receptor Tyrosine Kinase in Breast Cancer

2.0

$199,876

$189,882

$389,758

Smith, Jeffrey
Protease Fingerprinting to Diagnose Breast Cancer

2.0

$148,895

$136,510

$285,405

Strongin, Alex
Spatial Control of Matrix Proteolysis in Breast Cancer

2.0

$174,555

$165,828

$340,383

Sun, YingQing
A Novel Inhibitor of Breast Tumor Angiogenesis

2.0

$70,000

$5,600

$75,600

Vuori, Kristiina
How Does Endostatin Inhibit Breast Cancer Angiogenesis?

2.0

$150,022

$142,521

$292,543

SUBTOTAL

 

$962,978

$788,089

$1,751,067

 

University of California, Berkeley

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Firestone, Gary
Indole Derivatives as Novel Breast Cancer Therapeutics

2.0

$150,000

$0

$150,000

Miller, Sheldon
Mechanisms of Fluid Transport in Human Mammary Epithelium

2.0

$149,822

$0

$149,822

Zhang, Liqun JoAnn
How Indole-3 Carbinol Inhibits Breast Cancer Cell Growth

2.0

$70,000

$0

$70,000

SUBTOTAL

 

$369,822

$0

$369,822

 

University of California, Davis

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Cardiff, Robert
Oncogenes: Progression and Biomarkers

2.0

$144,609

$0

$144,609

Melnikow, Joy
Tamoxifen Prevention: Is it Acceptable to Women at Risk?

2.0

$321,373

$0

$321,373

Winthrop, Michelle
Bispecific Antibodies for Radiotherapy of Breast Cancer

2.0

$70,000

$0

$70,000

SUBTOTAL

 

$535,982

$0

$535,982

 

University of California, Irvine

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Michelle Tabb
SXR: A Novel Target for Breast Cancer Therapeutics

2.0

$70,000

$0

$70,000

 

University of California, Los Angeles

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Barsky, Sanford
A New Model for Inflammatory Breast Carcinoma

2.0

$200,000

$0

$200,000

Gallardo, Nilsa
Social Support and Breast Cancer Control Among Latinas

2.0

$70,000

$0

$70,000

Kagawa-Singer, Marjorie
Breast Health Project for Hmong Women and Men

3.0

$500,000

$0

$500,000

Kimme-Smith, Carolyn
UCLA Biomedical Physics Graduate Training in Breast Cancer

3.0

$189,206

$0

$189,206

Nguyen, Mai
Novel Breast Cancer Anti-Angiogenic Compounds

1.0

$69,227

$0

$69,227

Pietras, Richard
New Radiation Therapy for HER-2-overexpressing Breast Cancer

2.0

$200,000

$0

$200,000

Premack, Brett
Role of Chemokine Receptors in Breast Cancer Metastasis

1.0

$49,966

$0

$49,966

SUBTOTAL

 

$1,278,399

$0

$1,578,399

 

University of California, Riverside

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Byus, Craig
Unique Genes Expressed in Cancer Cells

2.0

$150,000

$0

$150,000

 

University of California, San Diego

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Andersen, Bogi
New Gene Regulation Factor, LMO-4, in Breast Cancer

2.0

$190,000

$0

$190,000

MacLeod, Carol
The Role of Nitric Oxide and Arginine in the Normal and Tumorous Breast

2.0

$200,000

$0

$200,000

Xu, Yang
The Regulation of p53 Activity in Breast Cancer

2.0

$181,560

$0

$181,560

SUBTOTAL

 

$571,560

$0

$571,560

 

University of California, San Francisco

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Beyene, Yewoubdar
Beliefs and Risks of Breast Cancer Among African Immigrants

2.0

$112,620

$0

$112,620

Campbell, Michael
HER2/Neu DNA Vaccines for Breast Cancer

2.0

$197,249

$0

$197,249

Lieberman, Morton
Effectiveness of Electronic Support Groups for Breast Cancer

1.0

$100,000

$0

$100,000

Tripathy, Debasish
Laboratory Testing of Chinese Herbs Used for Breast Cancer

1.0

$95,593

$0

$95,593

Wrensch, Margaret
Marin County Breast Cancer Study of Adolescent Risk Factors

2.5

$284,905

$0

$284,905

SUBTOTAL

 

$790,367

$0

$790,367

 

University of Southern California

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Bernstein, Leslie
Postmenopausal Breast Cancer: Obesity and the Leptin Receptor Gene

1.0

$74,938

$47,586

$122,524

Hamilton, Ann
Breast Cancer Susceptibility Genes in Very High Risk Women

1.0

$80,243

$50,954

$131,197

Henderson, Brian
IGF System and Breast Cancer in Postmenopausal Women

1.0

$74,956

$47,597

$122,553

Meyerowitz, Beth
Breast Cancer Survivorship: Partner's Role in Recovery

3.0

$468,018

$150,320

$618,338

Press, Michael
Can Molecular Markrs Predict Response to Adjuvant Therapy?

3.0

$312,670

$198,085

$510,755

Williams-Hill, Donna
Exercise, Hormones and Breast Cancer Prevention

1.0

$87,126

$55,325

$142,451

Wu, Anna
Estrogen-metabolizing Genes, Soy and Breast Cancer in Asians

3.0

$1,023,306

$646,221

$1,669,527

SUBTOTAL

 

$2,121,257

$1,196,088

$3,317,345

 

Women's Cancer Resource Center

DURATION

DIRECT COST

INDIRECT COST

TOTAL

Estrin, Diane
Returning to Work and Quality of Life After Breast Cancer

1.0

$74,910

$11,237

$86,147

Eversley, Rani
(Sub-contract to Women's Cancer Resource Center)

1.0

$0

$0

$0

SUBTOTAL

 

$74,910

$11,237

$86,147